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目的分析ＩＨＡ法在湖区血吸虫病中度流行区确定化疗对象的可靠性。方法选择洞庭湖沿岸疫情基本一致的流行村６个，居民感染率均在１０％～１５％之间。每年对其一半人群采用ＩＨＡ法过筛，抗体滴度在１： １０及以上者作为化疗对象，同时用Ｋａｔｏ－Ｋａｔｚ粪检法考核化疗效果。结果ＩＨＡ法阳性者包括了９０．７％～９６．１％的Ｋａｔｏ－Ｋａｔｚ粪检阳性者在内。１９９７、１９９８年ＩＨＡ和粪检都为阳性的人群，１９９９年粪检阴转率为８０．５％和７７．７％。ＩＨＡ和粪检均为阴性的人群，粪检考核阴性率仍保持９６．４％到 ９８． ３％。单就１９９７年粪检阳性者而言，１９０９年粪检阴转率为 ７４． ４％。结论在湖区血吸虫病中度流行区，采用ＩＨＡ确定化疗对象，可将９０％以上的粪检阳性对象和粪检查不出的大量血吸虫病人包括在内，其阳性和阴性结果是可靠的。
Objective To analyze the reliability of the IHA method for determining the chemotherapeutic agents in the endemic areas of schistosomiasis in the lake area. Methods Six endemic villages with the same epidemic situation along the coast of Dongting Lake were selected, and the infection rate among residents was between 10% and 15%. Half of the population is screened by IHA every year for whom antibody titer is 1: 10 and above, and Kato-Katz fecal test to assess the effect of chemotherapy. Results IHA positive patients included 90.7% ~ 96.1% of Kato-Katz stool positive. In 1997 and 1998, IHA and manure were both positive. In 1999, the fecal negative conversion rates were 80.5% and 77.7% respectively. IHA and fecal examination were negative for the crowd, fecal examination negative rate remained at 96.4% to 98. 3%. In the case of positive stool tests in 1997 alone, the negative rate of excrement detection in 1909 was 74. 4%. Conclusions In the moderately endemic area of schistosomiasis in the lake, using IHA to determine the target of chemotherapy can include more than 90% of the fecal positive samples and large numbers of schistosomiasis not detected, and the positive and negative results are reliable.