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甲状旁腺激素(PTH)和降钙素(CT)是体内调节钙、磷代谢的两个主要因素。PTH可以促进骨盐的溶解,使血钙升高;CT可以刺激钙盐的沉积,使血钙降低。近年来,许多作者报告,糖尿病患者常伴有钙、磷代谢的紊乱,引起骨质疏松,产生糖尿病骨病。但其发病机制目前尚不十分了解。本工作应用PTH和CT的放射免疫测定方法,观察33例糖尿病患者血清中PTH和28例CT的含量变化。对象和方法对象:33例患者均依1981年兰州糖尿病会议制定的标准进行诊断。其中男16例,女17例。平均年龄49.7岁,其中30～50岁24例(占73％)。平均病
Parathyroid hormone (PTH) and calcitonin (CT) are two major factors that regulate calcium and phosphorus metabolism in vivo. PTH can promote the dissolution of bone salt, so that elevated serum calcium; CT can stimulate the deposition of calcium, so that serum calcium decreased. In recent years, many authors report that diabetic patients are often accompanied by disorders of calcium and phosphorus metabolism, causing osteoporosis and producing diabetic bone disease. But its pathogenesis is not yet well understood. The application of PTH and CT radioimmunoassay, 33 cases of diabetic patients with PTH and 28 cases of CT changes. Subjects and Methods Subjects: All 33 patients were diagnosed according to the criteria established by the Lanzhou Diabetes Conference in 1981. There were 16 males and 17 females. The average age of 49.7 years, of which 30 to 50 years old in 24 cases (73%). Average disease