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目的探讨染色体多态性对IVF/ICSI-ET妊娠结局的影响。方法回顾性分析271对行IVF/ICSI-ET治疗患者的染色体核型,分为多态性组和正常组,并对两组间的胚胎种植率、临床妊娠率和早期流产率等临床资料进行比较。结果染色体多态性组与正常组相比,胚胎种植率(36.3%vs 33.4%)、临床妊娠率(50.6%vs 47.5%)和早期流产率(10.8%vs12.2%)无统计学差异(P>0.05)。结论染色体多态性对于IVF/ICSI-ET治疗患者的胚胎种植率、临床妊娠率和早期流产率均无明显影响。
Objective To investigate the effect of chromosome polymorphism on IVF / ICSI-ET pregnancy outcome. Methods The chromosomal karyotypes of 271 patients with IVF / ICSI-ET were retrospectively analyzed and divided into polymorphism group and normal group. Clinical data such as embryo implantation rate, clinical pregnancy rate and early abortion rate were compared between the two groups Compare Results There were no significant differences in embryo implantation rate (36.3% vs 33.4%), clinical pregnancy rate (50.6% vs 47.5%) and early miscarriage rate (10.8% vs12.2%) in the chromosome polymorphism group P> 0.05). Conclusions Chromosomal polymorphism has no significant effect on embryo implantation rate, clinical pregnancy rate and early abortion rate in IVF / ICSI-ET patients.