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测定了６５２例贵阳地区汉族及少数民族孕妇静脉血中巨细胞病毒（ＣＭＶ）、风疹病毒（ＲＶ）、单纯疱疹病毒（ＨＳＶ）、弓形虫（Ｔｇ）的特异性抗体，发现抗体阳性率高，ＲＶ及ＨＳＶＩｇＧ阳性有民族差异性（Ｐ＜０．０５），ＲＶＩｇＧ及ＩｇＭ阳性有年龄差异（Ｐ＜０．０５），ＣＭＶＩｇＭ阳性有年龄差异（Ｐ＜０．０１），ＣＭＶＩｇＧ阳性有孕期差异（Ｐ＜０．０１）。同时配对测定母血与脐血５９例，发现３例病毒ＩｇＭ阳性及１例ＴｇＣＡ阳性的孕妇其新生儿脐血中ＩｇＭ及ＴｇＣＡ也阳性，提示病原体可直接通过胎盘感染胎儿。发现孕妇有上述４种病原体混合感染，混合感染无民族差异，认为ＲＶ、ＣＭＶ、ＨＳＶ、Ｔｇ作为孕妇的常规检测项目有重要意义，尤其是感染高发的年龄和孕期
The specific antibodies against CMV, RV, HSV and Toxoplasma gondii in venous blood of 652 Han and minority pregnant women in Guiyang were determined and the positive rate of antibody was high. (P <0.05), RVIgG and IgM positive had age difference (P <0.05), CMVIgM positive age difference (P <0.01), CMVIgG positive had difference in pregnancy (P < P <0.01). In the meantime, maternal blood and umbilical cord blood were mated in 59 cases. Three positive IgM and one positive TgCA were found in neonates with positive IgM and TgCA in cord blood, suggesting that the pathogen could directly infect the fetus through the placenta. Found that pregnant women have the above four kinds of pathogens mixed infection, mixed infection without national differences, that RV, CMV, HSV, Tg as a routine test of pregnant women is important, especially in highly infected age and pregnancy