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目的:探讨急性肺损伤(ALI)、急性呼吸窘迫综合征(ARDS)、全身炎症反应综合征(SIRS)和多器官功能障碍综合征(MODS)的临床意义,并观察ARDS的酸碱失衡类型及糖皮质激素的疗效。方法:回顾性研究临床病例。结果和结论:①ARDS患者病死率(51.3%)显著高于ALI(20.5%),提示区分ALI与ARDS对于临床防治具有一定意义;②感染和创伤是诱发SIRS的常见因素,SIRS的严重程度与MODS的发生及ALI和ARDS的预后有关;③ARDS患者的酸碱失衡发生率高达98.3%,并以混合性酸碱失衡常见;④对于感染性ARDS,在有效控制感染下,使用肾上腺皮质激素可能改善预后。
Objective: To investigate the clinical significance of acute lung injury (ALI), acute respiratory distress syndrome (ARDS), systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) Efficacy of glucocorticoids. Methods: A retrospective study of clinical cases. RESULTS AND CONCLUSION: ① The mortality of ARDS patients was significantly higher than that of ALI patients (51.3% vs 20.5%), suggesting that it was meaningful to distinguish between ALI and ARDS. ② Infection and trauma were common factors in SIRS. The severity of MODS and the occurrence of ALI and ARDS prognosis; ③ ARDS patients with acid-base imbalance rate as high as 98.3%, and mixed acid-base imbalance is common; ④ Infectious ARDS, in the effective control of infection, the use of Cortisol may improve the prognosis.