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目的评价卡托普利和硝苯地平缓释片治疗高血压病的临床疗效。方法 300例原发性高血压患者随机分成三组,分别观察三组治疗前后所有参与者血压心率的变化。结果监测血压显示联合治疗组的收缩压、舒张压及心率与其他两组治疗后比较,差异有统计学意义,硝苯地平缓释片组降压与卡托普利组无差异,三组在调整心率稳定方面的疗效差异无统计学意义。结论卡托普利加硝苯地平缓释片联合应用治疗高血压的疗效确切,不良反应小,值得推广使用。
Objective To evaluate the clinical efficacy of captopril and nifedipine sustained-release tablets in the treatment of hypertension. Methods Three hundred patients with essential hypertension were randomly divided into three groups. The changes of blood pressure and heart rate were observed in all three groups before and after treatment. Results Blood pressure monitoring showed systolic blood pressure, diastolic blood pressure and heart rate in the combined treatment group were significantly different from those in the other two groups. There was no difference between the nifedipine sustained release group and the captopril group. No significant difference was found in the efficacy of adjusting heart rate. Conclusion Captopril plus nifedipine sustained-release tablets in combination with the treatment of hypertension is effective and has a small adverse reaction, which is worth promoting.