论文部分内容阅读
目的:探讨巨块型宫颈癌IB-IIB期术前应用口服氟铁龙及区域性化疗的临床意义.方法:22例宫颈肿瘤大于5cm的stageIB-IIB宫颈癌患者均接受术前口服5’-DFUR 800mg/m~2/天×14天为一疗程第29天再重复.介入化疗,导管超选择至子宫动脉,注入顺铂30mg/m~2/例,表阿霉素25mg/m~ 2/例,第2周为一疗程,共2～3疗程.然后全组病人均行宫颈癌根治术.结果:经术前化疗后宫颈局部肿瘤明显缩小,PR为100%,为彻底手术奠定基础,并使原不能手术者亦成为手术可能.结论:术前化疗对巨块型宫颈癌疗效明显.
Objective: To investigate the clinical significance of preoperative application of oral isonon and regional chemotherapy in IB-IIB patients with giant-type cervical cancer.Methods: Twenty-two patients with stage IB-IIB cervical cancer with cervical cancer larger than 5 cm were treated with preoperative oral 5’- DFUR 800mg / m ~ 2 / day × 14days was repeated on the 29th day of treatment.After chemotherapy, the catheter was superselected to the uterine artery and injected with cisplatin 30mg / m ~ 2 / case, epirubicin 25mg / m ~ 2 / Cases, the first two weeks for a course of treatment, a total of 2 to 3 courses.And then all patients underwent cervical cancer radical surgery.Results: After preoperative chemotherapy cervical local tumor was significantly reduced, PR was 100%, to lay the foundation for radical surgery , And make the original can not surgery also become a surgery possible.Conclusion: Preoperative chemotherapy for giant type of cervical cancer has obvious curative effect.