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细胞凋亡(apoptosis)与肿瘤的发生、发展和转移有密切关系,诱导肿瘤细胞凋亡以达到治疗目的是近几年肿瘤治疗的热点之一。肿瘤坏死因子相关的凋亡诱导配体(TNF-re-lated apoptosis-inducing ligand,TRAIL)是新近发现的TNF超家族成员,它能选择性的诱导肿瘤细胞和转化细胞发生凋
Apoptosis is closely related to tumorigenesis, development and metastasis. Inducing apoptosis of tumor cells for therapeutic purposes has been one of the hot spots for cancer therapy in recent years. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a recently discovered member of the TNF superfamily that selectively induces apoptosis in tumor cells and transformed cells