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系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种好发于育龄期女性的自身免疫性疾病,可累及全身各个系统,其中血液系统的损害仅次于肾脏损害居第二位,临床表现为贫血、白细胞及血小板减少。血小板(PLT)减少是系统性红斑狼疮主要并发症之一,发生率约为7%~30%[1],我国有文献报道发生率约19%[2],但仅5%的病人出现严重血小板减少(≤20×109L-1)。PLT减少也是SLE预后不良的一个独立危险
Systemic lupus erythematosus (SLE) is an autoimmune disease that occurs in women of childbearing age and can affect various systems of the whole body. The blood system damage is second only to that of kidney damage. The clinical manifestations are Anemia, white blood cells and thrombocytopenia. Platelet (PLT) reduction is one of the major complications of systemic lupus erythematosus, the incidence of about 7% to 30% [1], our country has reported about 19% of the incidence of [2], but only 5% of patients with serious Thrombocytopenia (≤20 × 109L-1). PLT reduction is also an independent risk of poor prognosis of SLE