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休克的液体复苏研究持续了20多年,近10年来的研究无论是晶体液或胶体液其容量复苏的近期效果已获得肯定,而更多的研究关注:(1)复苏维持的时间或者是复苏液体再分布及代谢问题。(2)休克时除外补充容量后,机体病理生理改变所产生的其他需要,如晶体、胶体渗透压的要求、较少毛细血管通透性的要求等。(3)对血液各成分功能的保护问题,如凝血功能、免疫功能。(4)复苏的一些远期效果,如较少炎症反应或组织再灌注损伤问题、器官功能保护问题。6%羟乙基淀粉(HES)盐水溶液——HES130/0.4(万汶)、琥珀酸明胶(佳乐施)或一定比例的高渗透压的晶体和胶体混合液,都被发现各自的优缺点,为各类型休克包括出血性休克、脓毒性休克、心源性休克的个体化复苏方案提供了药物选择的参考依据。
The research of liquid resuscitation in shock lasted more than 20 years. The recent researches on the capacity resuscitation of crystalloid or colloidal fluid have been affirmed in the recent 10 years, and more researches focus on the following aspects: (1) the time of resuscitation or resuscitation liquid Redistribution and metabolic problems. (2) other than the additional capacity after shock, the body caused by pathophysiological changes in other needs, such as crystal, colloid osmotic pressure requirements, less capillary permeability requirements. (3) the protection of the function of blood components, such as coagulation, immune function. (4) some of the long-term effects of recovery, such as less inflammation or tissue reperfusion injury problems, organ function protection problems. 6% Hydroxyethyl Starch (HES) saline solution - HES130 / 0.4 (Van Wensn), succinic acid gelatin (good Oxfam) or a certain proportion of high osmotic pressure crystal and colloidal mixture were found to their respective advantages and disadvantages , For all types of shock, including hemorrhagic shock, septic shock, cardiogenic shock individualized recovery program provides a reference for drug selection.