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目的:分析武汉地区儿童肺炎支原体(MP)感染情况及流行现状分析。方法:收集2014-01-2014-12住院的20 630例呼吸道感染住院患儿的鼻咽拭子,采用实时荧光定量PCR法检测MP核酸,并对患儿的年龄、性别、患病时间以及临床症状等进行统计学分析。结果:20 630例呼吸道感染住院患儿中MP核酸阳性4 386例,阳性率为21.26%,春、夏、秋、冬四季的MP阳性率分别为19.44%,25.83%,20.41%,18.88%,以夏季阳性率最高;发病患儿年龄集中于3~6岁;临床表现主要有咳嗽和发热,少数有喘息,呼吸困难,肺部听诊可闻及啰音,肺外表现以胃肠道症状和皮肤损害为主。结论:武汉地区MP感染率与季节及患儿的年龄有关。
Objective: To analyze the status of Mycoplasma pneumoniae (MP) infection and prevalence in children in Wuhan. Methods: The nasopharyngeal swabs of 20 630 inpatients with respiratory tract infection who were hospitalized from January 2014 to December 2014 were collected. The MP nucleic acids were detected by real-time fluorescence quantitative PCR. The age, gender, duration of illness, Symptoms such as statistical analysis. Results: The positive rate of MP nucleic acid in 20 630 inpatients with respiratory tract infection was 4 386, with a positive rate of 21.26%. The positive rates of MP in spring, summer, autumn and winter were 19.44%, 25.83%, 20.41% and 18.88% respectively, The highest positive rate in summer; the incidence of children focused on the age of 3 to 6 years old; the main clinical manifestations of cough and fever, a few have wheezing, dyspnea, pulmonary auscultation may smell and rales, pulmonary manifestations of gastrointestinal symptoms and Mainly skin damage. Conclusion: The prevalence of MP infection in Wuhan is related to the season and the age of children.