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目的研究阿伦膦酸钠对绝经后妇女骨质疏松症的效果。方法对我院收治的绝经后骨质疏松症的妇女74例,随机分为实验组和对照组两组。其中对照组31人,实验组43人。然后对实验组服用阿仑磷酸钠,对照组服用钙尔奇D1分别进行治疗。两组对象从年龄、性别、症状及疼痛等方面均无显著差异,具有对照性。实验组每天一次晨起空腹服用阿仑磷酸钠10mg;对照组则每天一次晚餐后服用钙尔奇D1片,均是半年为一个疗程。然后对体质的改变、临床症状及腰椎骨密进行治疗前后的对比。结果经检测骨密度的提高,疼痛症状的减轻和时间的缩短,实验组均明显优于对照组(试验组的总有效率为97.7%;对照组的总有效率为48.34%),P<0.05,具有统计学意义。结论阿伦膦酸钠对绝经后妇女骨质疏松症治疗有显著疗效。
Objective To study the effect of alendronate on postmenopausal women with osteoporosis. Methods 74 cases of postmenopausal women with osteoporosis admitted to our hospital were randomly divided into experimental group and control group. Including 31 in the control group and 43 in the experimental group. Then the experimental group took alendronate, the control group took Calcium D1 separately for treatment. The two groups of subjects from the age, gender, symptoms and pain were no significant differences, with control. Experimental group once daily morning fasting alendronate 10mg; control group was once daily after dinner taking erqi D1 tablets, are six months for a course of treatment. Then the physical changes, clinical symptoms and lumbar bone density before and after treatment comparison. Results Compared with the control group, the total effective rate (97.7%) in the experimental group and the control group (48.34%) were significantly lower than those in the control group (P <0.05) ,has statistical significane. Conclusion alendronate has a significant effect on the treatment of osteoporosis in postmenopausal women.