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配子捐赠不是新的概念。供者人工授精治疗不孕症已有多年的历史。然而卵子的捐赠仅在体外受精技术发展后才成为可能。1983年Trounson等首先报告捐赠卵子后妊娠。几个月后Lutjen等报道捐赠卵子后妊娠并成功地分娩。此后类似报道不断出现。目前该项技术已成为下列三组妇女不孕症可行的治疗措施:①由于卵巢衰竭或切除引起性腺功能缺如;②标准体外受精技术未能收获足量卵母细胞;③因有遗传性疾病危险而不愿使用自身配子的妇女。上述后两组患者的卵巢功能往往正常,但①组妇女必须采用
Gametes donation is not a new concept. Donor artificial insemination has been in the history of infertility for many years. However, egg donation is only possible after in vitro fertilization. In 1983, Trounson et al. First reported pregnancy after egg donation. A few months later, Lutjen et al. Reported that they had donated their eggs for pregnancy and delivered them successfully. Since then similar reports continue to appear. At present, the technology has become a feasible treatment for infertility in the following three groups: ① lack of gonadal function due to ovarian failure or resection; ② failure of standard in vitro fertilization to harvest enough oocytes; ③ due to inherited diseases Women who are dangerous and do not want to use their own gametes. The latter two groups of patients often have normal ovarian function, but group ① women must be used