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目的了解浙江省杭州市西湖区男男性行为人群(MSM)同性性行为特征、感染风险情况、HIV感染情况及影响因素分析。方法本项目采用滚雪球和同伴推荐的非概率抽样方法在非政府组织中招募研究对象进行问卷调查,采用唾液快检试剂进行初筛,蛋白印迹试验(WB)进行实验室确证,logistic回归用于调查对象HIV感染影响因素的分析。结果共调查1 906人,唾液快检试剂检测结果显示有96人(占5.04%)HIV抗体阳性,阳性告知率89.63%;最终HIV确证阳性45人(占2.36%),阳性告知率100.00%。仅有110人(5.77%)每次发生性关系前知道对方HIV感染状况,1 054人(占55.30%)对在发生性关系前是否了解对方HIV感染情况持无所谓态度,649人(34.05%)认为自己不可能感染HIV,1 079人(56.61%)没想过这个问题。多因素logistic回归分析结果显示,近6个月与男性发生性交时从不使用安全套(OR=4.545,95%CI:1.093~18.894)、近6个月与男性发生性交时有时使用安全套(OR=3.134,95%CI:1.133~8.666)、从未做过HIV抗体检测(OR=37.027,95%CI:10.928~125.459)、只做过1~2次HIV抗体检测(OR=12.291,95%CI:3.338~45.254)、没有想过HIV感染风险问题(OR=5.792,95%CI:2.271~14.771)是HIV感染的危险因素。结论推广安全套的使用,提高艾滋病感染风险意识,并且提高快检试剂初筛阳性人群的确诊比例是当前西湖区MSM艾滋病防治工作的重点。
Objective To investigate the characteristics of homosexual behaviors, the risk of infection, the prevalence of HIV infection and the influencing factors among men who have sex with men (MSM) in West Lake District, Hangzhou City, Zhejiang Province. Methods This project uses non-probabilistic sampling method recommended by snowballs and companion to conduct questionnaire survey among NGOs, preliminary screening with saliva fast test reagent, WB confirmation by laboratory, and logistic regression for investigation Analysis of Influencing Factors of HIV Infection in Subjects. Results A total of 1 906 people were tested. The results of saliva rapid test showed that 96 (5.04%) were HIV positive, the positive rate was 89.63%. The final HIV positive rate was 45 (2.36%), the positive rate was 100.00%. Only 110 people (5.77%) knew each other’s HIV status before each sexual intercourse, and 1,054 (55.30%) did not know whether they knew each other’s HIV status before having sex, 649 (34.05% I think I can not be infected with HIV, 1,079 people (56.61%) did not think about this issue. Multivariate logistic regression analysis showed that condoms were never used during intercourse with men in the past 6 months (OR = 4.545,95% CI: 1.093-18.894). Condoms were sometimes used during intercourse with men in the past 6 months (OR = (OR = 37.027, 95% CI: 10.928 ~ 125.459), only one or two HIV antibody tests (OR = 12.291, 95% CI: 3.134,95% CI: 1.133-8.666) : 3.338 ~ 45.254), and no thought of the risk of HIV infection (OR = 5.792, 95% CI: 2.271-14.771) was a risk factor for HIV infection. Conclusions The promotion of condom use, raising the awareness of HIV infection risk, and increasing the proportion of positive cases of positive screening tests for early screening reagents are the key points of MSM AIDS prevention and control in West Lake District.