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目的：研究萎缩性阴道炎患者的阴道菌群分布情况。方法：收集萎缩性阴道炎病人５０ 例、绝经前健康妇女３０ 例和绝经后阴道萎缩妇女２０ 例，进行阴道需氧菌和厌氧菌培养。结果：５０ 例萎缩性阴道炎组共分离出需氧菌６５ 株，分离率由高到低前４ 位依次是大肠埃希氏菌（１３／５０ ，２６ ％ ） 、表皮葡萄球菌（９／５０ ，１８ ％ ） 、粪链球菌（７／５０ ，１４ ％ ） 和绿色链球菌（６／５０ ，１２ ％ ） ，分离出厌氧菌５６ 株，分离率由高到低前４ 位依次是拟杆菌（２１／５０ ，４２ ％ ） 、消化链球菌（１９／５０ ，３８ ％ ） 和真杆菌（６／５０ ，１２ ％ ） 。除大肠埃希氏菌的分离率明显高于绝经前对照组外，其余各菌群与另外两组比较无明显差异， Ｐ ≤００５ 。结论：萎缩性阴道炎的菌群分布除大肠埃希氏菌外，其它菌群与绝经前妇女基本相似。
Objective: To study the distribution of vaginal flora in patients with atrophic vaginitis. Methods: 50 cases of atrophic vaginitis, 30 cases of premenopausal women and 20 cases of vaginal atrophy after menopause were collected for vaginal aerobic and anaerobic culture. Results: Among the 50 atrophic vaginitis groups, 65 strains of aerobic bacteria were isolated. The top 4 isolates were Escherichia coli (13/50, 26%), Staphylococcus epidermidis (9/50 , 18%), Streptococcus faecalis (7/50, 14%) and Streptococcus viridans (6/50, 12%) .And 56 strains of anaerobic bacteria were isolated. (21/50, 42%), Peptostreptococcus (19/50, 38%) and Eubacterium (6/50, 12%). In addition to the separation rate of Escherichia coli was significantly higher than the pre-menopausal control group, the rest of the flora and the other two groups no significant difference, P ≤ 0 05. Conclusion: The distribution of atrophic vaginitis flora except Escherichia coli, other flora and pre-menopausal women were similar.