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对６９例可手术的非小细胞肺癌病例，随机分组分成ＬＡＫ细胞＋ＩＬ－２治疗的研究组２３例，单纯手术的对照组４６例，采用多元方差和单因素方差的统计方法，分析术后辅助性ＬＡＫ细胞过继性免疫治疗对围术期非小细胞肺癌细胞免疫功能的影响。结果显示，对ＣＤ４，ＣＤ４／ＣＤ８比率、ＮＫ细胞活性和淋巴细胞转化率４个指标的综合分析，两组间在围术期不同时间段上的细胞免疫功能都无显著性差异（各组间的ＨｏｔｅｌｉｎｇＴ２检验，Ｐ值均大于０．０５），但研究组术后１２ｄ的ＮＫ细胞活性较术前下降（单因素方差分析Ｐ＜０．０５），与对照组比较，差异也有统计学上的显著性意义（多元方差分析Ｆ＝４．５７１１，Ｐ＜０．０５）。
69 cases of operable non-small cell lung cancer cases were randomly divided into two groups: LAK cells + IL-2 treatment group: 23 cases, and surgery-only control group 46 cases. Multivariate analysis of variance and one-way variance were used to analyze postoperative assistants. Effect of adoptive immunotherapy with LAK cells on the immune function of non-small cell lung cancer during perioperative period. The results showed that there was no significant difference in cell immune function between the two groups at different time periods during the perioperative period, based on a comprehensive analysis of the CD4, CD4/CD8 ratio, NK cell activity, and lymphocyte transformation rate. In the Hoteling T2 test, the P value was greater than 0.05, but the NK cell activity at the 12th day after surgery in the study group was lower than before surgery (one-way ANOVA) (P<0.05). Compared with the control group, the difference was also statistically significant. Significant significance (multivariate analysis of variance F = 4.5711, P < 0.05).