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目的探讨手术切除及联合放化疗治疗腭部涎腺肿瘤的临床疗效。方法收集95例涎腺肿瘤患者的临床资料进行回顾性分析,其中单纯手术切除治疗69例,手术联合放化疗治疗26例。观察本组患者的复发情况。结果采用单纯手术切除治疗的患者13例复发,均为多形性腺瘤,复发率为18.8%;采用手术切除联合放化疗治疗的患者11例复发,其中腺样囊性癌6例,恶性多形性腺瘤4倒,粘液表皮样癌1例,复发率为42.3%。结论对腭部涎腺肿瘤的治疗,若为良性肿瘤,主要采用单纯手术切除,能获得较低的复发率;若为恶性肿瘤,应以手术切除为主,配合放化疗治疗,尽可能降低复发率。
Objective To investigate the clinical effects of surgical resection combined with radiotherapy and chemotherapy on palatal salivary gland tumors. Methods The clinical data of 95 patients with salivary gland tumors were retrospectively analyzed. Among them, 69 cases were treated by simple surgical resection and 26 cases were treated by combined surgery and radiotherapy. Observe the recurrence of this group of patients. Results Thirteen cases of recurrent adenomas were pleomorphic adenomas with a recurrence rate of 18.8%. Surgical resection combined with chemoradiotherapy in 11 patients with recurrent adenocarcinoma, including 6 adenoid cystic carcinomas, malignant polymorphisms 4 down adenoma, mucoepidermoid carcinoma in 1 case, the recurrence rate was 42.3%. Conclusions The treatment of palatal salivary gland tumors, if benign, is mainly performed by simple surgical resection and can achieve a low recurrence rate. If malignant tumors are treated by surgical resection, radiotherapy and chemotherapy should be used to minimize recurrence rate.