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目的观察醋酸奥曲肽治疗各种原因引起的上消化道大出血的疗效。方法对56例上消化道大出血患者回顾性分析和总结,采用奥曲肽0.1mg配生理盐水20ml静脉缓慢推注,再以0.025mg/h静脉滴注24～72h。结果24h及72h止血率分别为53.6%和42.8%,3d总有效率为96.4%。未发现明显不良反应。结论奥曲肽治疗上消化道大出血止血效果显著,使用安全,在基层医院临床急救中应及早使用。
Objective To observe the curative effect of octreotide acetate on various causes of upper gastrointestinal hemorrhage. Methods 56 patients with upper gastrointestinal bleeding were retrospectively analyzed and summarized. The patients were given 0.1 mg octreotide with 20 ml intravenous bolus and then with 0.025 mg / h intravenously for 24-72 hours. Results The hemostatic rates at 24h and 72h were 53.6% and 42.8%, respectively, and the total effective rate at 3d was 96.4%. No obvious adverse reactions were found. Conclusion Octreotide treatment of upper gastrointestinal bleeding to stop bleeding is significant, safe to use, and should be used as soon as possible in the first aid of primary hospital.