论文部分内容阅读
已知RU486可增加早孕妇女子宫对阴道或肌肉给与前列腺素E(PGE)类似物兴奋作用的敏感性。为了验证RU486是否也增加子宫对口服一种PGE 类似物的敏感性,作者研究了两种给药方法。①对用或不用RU486的早孕妇女在给与9-次甲基PGE_2前后直接观察子宫收缩状况。②早孕妇女(闭经≤49天)每天两次应用RU486 25mg 共3或4天,随后应用9-次甲基PGE 22.5、5.0或10mg。
RU486 is known to increase the sensitivity of pregnant women’s wombs to the vaginal or muscular stimulation of prostaglandin E (PGE) analogs. To test whether RU486 also increases the sensitivity of the uterus to oral administration of a PGE analogue, the authors studied two administration methods. ① with or without RU486 in pregnant women before and after giving 9-methyl PGE_2 directly observe the uterine contractions. ② Early pregnant women (amenorrhea ≤ 49 days) RU486 25mg twice daily for 3 or 4 days, followed by 9-Methyl PGE 22.5,5.0 or 10mg.