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目的分析2012年理塘县人间鼠疫疫情,为人间鼠疫处置提供科学依据。方法运用流行病学调查方法,并结合临床表现和实验室检测结果。结果从死者的右腋下淋巴穿刺液、右腋下淋巴结、肋骨和皮下血棉拭子分离出鼠疫菌;自毙喜马拉雅旱獭股骨分离出鼠疫菌;IHA检测血清52份,结果均为阴性;RIHA检测人体及旱獭标本悬液10份,阳性8份,最高滴度为1∶40 960。结论通过流行病学调查、临床表现和实验室检测结果,确认死者是感染鼠疫菌而引起腺鼠疫继发败血型鼠疫导致死亡;在自毙旱獭分离出鼠疫菌确定理塘县为鼠疫自然疫源地,动物鼠疫流行猛烈,人间鼠疫和动物间鼠疫并发。
Objective To analyze the epidemic situation of human plague in Litang County in 2012 and provide a scientific basis for human plague disposition. Methods Epidemiological survey methods, combined with clinical manifestations and laboratory test results. Results Yersinia pestis was isolated from the right underarm lymphatic fluid, right underarm lymph node, rib and subcutaneous cotton swab. The Yersinia pestis was isolated from the femur of the Himalayan marmot. 52 serum samples were obtained by IHA, and the results were negative. The RIHA 10 samples of human and Marmot were tested for positive 8 copies with the highest titer of 1:40 960. Conclusions Epidemiological investigation, clinical manifestations and laboratory test results confirm that the deceased was infected with Yersinia pestis and caused the death of the plague of plague secondary to the bubonic plague. In the meantime, plague isolates from Litophyllum were identified as the natural epidemic of plague In the past, the fierce epidemic of animal plague, the plague of human beings and the epidemic of plague in animals.