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目的分析CT灌注成像与普通增强CT成像在脑胶质瘤边界确定中的差异性。方法分析41例经病理证实的脑胶质瘤患者的CT灌注及普通增强CT资料,并分别勾画、测量胶质瘤面积,采用SPSS15.0统计软件包,对两种方法分别获得二组病灶截面面积做配对t检验。结果两种方法确定的肿瘤面积差异有统计学意义(P<0.05),CT灌注成像确定的肿瘤面积术前组为(11.20±3.44)cm2;术后组为(10.99±2.57)cm2,普通增强CT成像确定的肿瘤面积术前组为(10.25±3.47)cm2,术后组为(9.76±2.46)cm2,CT灌注成像所确定的肿瘤边界明显大于普通增强CT所确定的肿瘤面积。结论 CT灌注成像可有效的评价胶质瘤的血流动力学特征,以灌注功能图PS图为参考勾画肿瘤的范围可较常规增强CT更好的反映肿瘤的浸润范围,有助于指导胶质瘤临床治疗。
Objective To analyze the difference between CT perfusion imaging and general enhanced CT in the determination of glioma border. Methods The CT perfusion and CT data of 41 patients with pathologically confirmed glioma were analyzed. The area of glioma was plotted and measured respectively. Using SPSS15.0 statistical software package, two groups of lesion cross sections Area do paired t test. Results The tumor area determined by the two methods was statistically significant (P <0.05). The area of tumor preoperatively determined by CT perfusion imaging was (11.20 ± 3.44) cm2 in the preoperative group and (10.99 ± 2.57) cm2 in the postoperative group, The tumor area determined by CT imaging was (10.25 ± 3.47) cm2 in the preoperative group and (9.76 ± 2.46) cm2 in the postoperative group. The tumor boundary determined by CT perfusion imaging was significantly larger than that of the contrast-enhanced CT. Conclusion CT perfusion imaging can effectively evaluate the hemodynamic characteristics of glioma, perfusing the PS chart as a reference for mapping the scope of the tumor can enhance the CT better than conventional CT to reflect the extent of tumor infiltration, help to guide the glial Tumor clinical treatment.