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目的探讨青年胃癌临床表现、胃镜检查及其病理、治疗及预后特点。方法回顾性分析我院2003年01月至2010年12月收治胃癌患者的临床资料。比较年龄≤40岁青年胃癌与年龄>40岁中老年胃癌患者的性别构成、发病情况、自觉症状到胃镜诊断病程、临床症状、肿瘤部位、临床分型、临床分期、病理类型、手术治疗、生存期随访情况等方面上的差异。结果青年组与中老年组比较女性占比例较高,上腹痛、腹块多见,确诊时间晚,胃窦癌发病率高,低-未分化腺癌、印戒细胞癌比例高,Ⅲ～Ⅳ期居多,根治性切除率低,生存期短;而上腹饱胀、消瘦、胃底贲门癌、高分化腺癌低于老年组。结论青年胃癌较老年恶性程度高、分化程度低、病程进展快、预后差,临床医生应提高对青年人胃癌的认识及警惕性,胃镜检查为首选,对于青年胃癌只要条件许可应以择期手术为主。
Objective To investigate the clinical manifestations, gastroscopy, pathology, treatment and prognosis of young patients with gastric cancer. Methods The clinical data of patients admitted to our hospital from January 2003 to December 2010 were retrospectively analyzed. To compare the gender composition, incidence, subjective symptoms to gastroscopy diagnosis, clinical symptoms, tumor location, clinical classification, clinical stage, pathological type, surgical treatment, survival of young patients with gastric cancer and younger than 40 years old with gastric cancer. Period of follow-up and other aspects of the difference. Results The proportion of females in the young and middle-aged groups was higher, with more abdominal pain and abdominal masses. The diagnosis was delayed. The incidence of gastric antrum cancer was high, and the proportion of low-undifferentiated adenocarcinomas and signet-ring cell carcinomas was high. III-IV Most of the period, radical resection rate is low, short survival time; and abdominal fullness, weight loss, gastric cardia cancer, well-differentiated adenocarcinoma is lower than the elderly group. Conclusions Young patients with gastric cancer have higher malignancy, poor differentiation, rapid progression, and poor prognosis. Clinicians should increase their awareness and vigilance of gastric cancer in young people. Gastroscopy is the first choice. For young patients with gastric cancer, elective surgery should be used as long as the conditions permit. the Lord.