踝臂指数与冠状动脉粥样硬化及其危险因素的关系

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目的研究踝臂指数与冠状动脉粥样硬化及其危险因素的关系。方法对216例住院患者行选择性冠状动脉造影,用冠状动脉病变血管的数量和Gensini积分系统评价冠状动脉病变的严重程度。进行踝臂指数测定及动脉硬化的危险因素分析。结果冠状动脉正常组与冠状动脉病变组踝臂指数差异显著(P<0.001),冠状动脉造影积分越高,踝臂指数越小。以踝臂指数<0.9为二分类变量做Logistic回归分析,发现踝臂指数与性别、年龄、低密度脂蛋白、甘油三脂、吸烟量、糖尿病等相关。结论踝臂指数是动脉粥样硬化一个简单可靠的预测因子,低踝臂指数与性别、年龄、低密度脂蛋白、甘油三脂、吸烟量、糖尿病有相关性。 Objective To study the relationship between ankle brachial index and coronary atherosclerosis and its risk factors. Methods 216 cases of hospitalized patients underwent selective coronary angiography, the number of coronary lesions and Gensini integral system to assess the severity of coronary lesions. Ankle brachial index and arteriosclerosis risk factors were analyzed. Results There was a significant difference in ankle-brachial index between the normal coronary artery group and the coronary artery disease group (P <0.001). The higher the coronary angiography score, the smaller the ankle-brachial index. Logistic regression analysis showed that the ankle-brachial index was related to gender, age, LDL, triglyceride, smoking amount, diabetes and so on. Conclusions Ankle-brachial index is a simple and reliable predictor of atherosclerosis. The index of ankle-brachial index is related to sex, age, LDL, triglyceride, smoking amount and diabetes.
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