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目的:探讨三维适形放疗加后装腔内放疗治疗晚期宫颈癌的疗效。方法:140例晚期宫颈癌患者随机分成治疗组和对照组各70例。治疗组行三维适形放疗加腔内照射,三维适形放疗处方剂量45 Gy,内照射5~6次,A点总剂量75~81 Gy。对照组采用体外照射加腔内照射,用6 MV-X线前后对穿照射,全盆腔照射30 Gy后改为四野照射并同时行腔内照射6-8次,A点总剂量66~78 Gy。结果:治疗组与对照组总有效率分别为92.8%(65/70)和77.1%(54/70)。结论:采用三维适形放疗加内照治疗晚期宫颈癌,局控率与生存率较常规放疗好,值得临床推广。
Objective: To investigate the curative effect of three-dimensional conformal radiotherapy plus endovascular radiotherapy for advanced cervical cancer. Methods: One hundred and forty patients with advanced cervical cancer were randomly divided into treatment group and control group, with 70 cases each. The treatment group underwent three-dimensional conformal radiotherapy plus intracavitary irradiation. The dose of three-dimensional conformal radiotherapy was 45 Gy and the internal irradiation was 5 to 6 times. The total dose of point A was 75-81 Gy. The control group was treated with irradiation in vitro and by intracavitary irradiation. The 6 MV-X line was worn before and after irradiation. After the whole pelvis was irradiated with 30 Gy, the control group was changed to Shuxu radiation and the irradiation was performed 6-8 times. The total dose of point A was 66-78 Gy. Results: The total effective rates of the treatment group and the control group were 92.8% (65/70) and 77.1% (54/70), respectively. Conclusion: Three-dimensional conformal radiotherapy combined with internal control in the treatment of advanced cervical cancer, local control rate and survival rate than conventional radiotherapy is worthy of clinical promotion.