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美国目前已逾一千万人作了输精管结扎手术,一些术后近期副作用,如伤口感染、附睾炎、血肿、性机能障碍等,已有报导;远期效果如何还不明确。有人对结扎后的罗猴作了长期观察,发现对精子抗原的免疫反应,可能会加速动脉硬化。人类精子抗体出现于手术后6周至6个月,而且抗体滴度升高可以持续许多年。这种自家免疫反应,各人并不相同,很可能取决于免疫反应基因。本文对作过冠状动脉造影的白人作了统计分析,探讨结扎和未结扎病人中,冠状动脉硬化程度是否有所不同。
At present, more than 10 million people in the United States have undergone vasectomy. Some short-term postoperative side effects such as wound infection, epididymitis, hematoma, and sexual dysfunction have been reported. The long-term effect is not yet clear. Long-term observation has been made on the rhesus monkey after ligation and the immune response to sperm antigens has been found to accelerate atherosclerosis. Human sperm antibodies appear 6 to 6 months after surgery, and antibody titers can persist for many years. This home-made immune response, different from person to person, probably depends on the immune response genes. This article made a statistical analysis of white coronary artery angiography to explore whether the degree of coronary atherosclerosis in patients with ligation and non-ligation is different.