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评价阻塞性睡眠呼吸暂停综合征（ＯＳＡＳ）与夜间多尿症状的关系。采用病例－对照研究方法研究６１例ＯＳＡＳ与４７例对照组、９例ＯＳＡＳ持续气道正压（ＣＰＡＰ）患者治疗前后夜间多尿症状的变化，及部分ＯＳＡＳ和对照者的夜尿量比较。结果：ＯＳＡＳ患者夜尿次数显著增多（χ２＝３３．６２，Ｐ＜０．０１），其发生夜间多尿症状的危险性是对照组的１２．９倍（ＯＲ＝１２．９，９５％可信区间为５．４～３０．６）；ＯＳＡＳ患者夜尿量明显增多（ｔ＝５．８３，Ｐ＜０．０１）；ＣＰＡＰ患者治疗后夜间多尿症状明显好转（Ｐ＝０．００１）。结论：夜间多尿症状与ＯＳＡＳ患者的睡眠呼吸暂停有关，ＣＰＡＰ治疗可改善之。
To evaluate the relationship between obstructive sleep apnea syndrome (OSAS) and nocturnal polyuria. A case-control study was conducted to investigate the changes of nocturnal polyuria in 61 patients with OSAS and 47 controls, and 9 patients with OSAS before and after CPAP. Nocturnal excretion of some OSAS and controls were compared. Results: The frequency of nocturnal urination in OSAS patients increased significantly (χ2 = 33.62, P <0.01). The incidence of nocturnal polyuria was 12.9 times more likely in the control group (OR = 12.9, 95% (T = 5.83, P <0.01). The symptoms of nocturnal polyuria in CPAP patients were significantly improved after treatment (P = 0.001) . Conclusions: Nighttime polyuria is associated with sleep apnea in patients with OSAS, and CPAP may improve the symptoms.