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日本 Kyowa公司正在开发一种可产生高活性抗体 ( Ab)的新方法 ,它将作为公司的核心技术用于制备新型治疗性 Ab。这项技术可使具有强烈细胞介导的细胞毒性( ADCC)的 Ab制品进行商品化生产。降低 Ab中岩藻糖量能增强 ADCC的活性。动物研究证实 ,此法生产的 Ab的抗肿瘤作用比传统
Japan Kyowa company is developing a new method to produce highly active antibodies (Ab), which will serve as the company’s core technology for the preparation of a new type of therapeutic Ab. This technology allows the commercial production of Ab preparations with strong cell-mediated cytotoxicity (ADCC). Decreasing the amount of fucose in Ab can enhance ADCC activity. Animal studies confirm that the anti-tumor effect of Ab produced by this method is more traditional