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目的:探讨利巴韦林气雾剂治疗婴幼儿手足口病(HFMD)Ⅰ期的临床疗效。方法:选取100例手足口病Ⅰ期患儿随机分为治疗组和对照组,对照组采用常规治疗及利巴韦林静滴治疗,治疗组在此基础上加用利巴韦林气雾剂口腔喷雾治疗,比较两组的临床疗效。结果:治疗组热退时间、疱疹消退时间、痊愈时间均短于对照组(P均<0.01),治疗组总有效率为92%,亦高于对照组76%。结论:利巴韦林气雾剂治疗手足口病Ⅰ期疗效确切,安全可靠,值得推广应用。
Objective: To investigate the clinical efficacy of ribavirin aerosol in the treatment of stage Ⅰ HFMD in infants. Methods: One hundred children with HFMD were randomly divided into treatment group and control group. The control group was treated with conventional therapy and ribavirin. The treatment group was treated with ribavirin aerosol Oral spray treatment, the clinical efficacy of two groups were compared. Results: The treatment group, the thermal back time, herpes regression time, recovery time were shorter than the control group (P all <0.01), the total effective rate was 92% in the treatment group, also higher than 76% in the control group. Conclusion: Ribavirin aerosol treatment of hand, foot and mouth disease stage Ⅰ effect is accurate, safe and reliable, it is worth to promote the application.