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目的分析影响宫腔内人工授精周期妊娠率的相关因素,以提高IUI治疗的临床效果。方法回顾性分析我院生殖科近5年来1224个宫腔内人工授精周期,探讨患者年龄、不孕原因、周期方案、精子回收率、排卵前卵泡直径、卵泡数目、卵泡是否破裂、子宫内膜形态与厚度、出血、漏出、授精次数等因素与妊娠率的关系。结果总妊娠率为12.6%(154/1224),logistic回归分析提示周期方案(OR:1.63,CI:1.10～2.41),精子回收率(OR:0.66,CI:0.46～0.96),卵泡是否破裂(OR:0.55,CI:0.28～0.91)显著影响IUI周期妇女妊娠率。结论促排卵及高精子回收率能提高IUI周期妊娠率,子宫内膜形态与厚度不影响妊娠率。
Objective To analyze the related factors that influence the pregnancy rate of intrauterine insemination in order to improve the clinical effect of IUI treatment. Methods A retrospective analysis of 1224 intrauterine insemination cycles in our hospital in the past five years was conducted to investigate the relationship between age, infertility causes, cycle plan, sperm recovery rate, ovulation follicle diameter, number of follicles, rupture of follicles, endometrium Morphology and thickness, bleeding, leakage, insemination frequency and other factors and the relationship between pregnancy rate. Results The total pregnancy rate was 12.6% (154/1224). Logistic regression analysis showed that the cycle program (OR: 1.63, CI: 1.10-2.41), sperm recovery (OR: 0.66, CI: 0.46-0.96) OR: 0.55, CI: 0.28-0.91) significantly affected the pregnancy rate in IUI women. Conclusion Ovulation and high sperm recovery rate can improve IUI cycle pregnancy rate, endometrial morphology and thickness does not affect the pregnancy rate.