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本文从探讨适合发酵液 CPCZn 盐含量分析的目的出发,利用高压液相色谱法所具有的分析速度快,灵敏度高,操作简单的特点,在生产中经过多次试验选择最佳操作条件,得到了可靠的分析结果,充分起到了指导工艺生产的作用。CPC—Zn 盐,是在发酵液中提取的 CPC,经过提炼制取的,它是多元化合物,它的组成中含有去乙酰头孢菌素 C,去乙酰氧头孢菌素 C 化合物,这些化合物各有与头孢菌素 C 类似的某些性质,在其它分析中都存在着测定繁锁或偏高的结果。
Based on the aim of analyzing the content of CPCZn suitable for fermentation broth, the high speed liquid chromatography with high sensitivity, high sensitivity and simple operation were selected. After several experiments, the optimal operating conditions were obtained and the optimum conditions were obtained Reliable analysis of the results, fully played a role in guiding the process of production. CPC-Zn salt is extracted from the fermentation broth CPC, after refining prepared, it is a multi-compound, its composition contains deacetylcephalosporin C, deacetoxycephalosporin C compounds, these compounds have Some properties similar to cephalosporin C, in other analyzes, are the result of cumbersome or high assay.