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Based on flip-chip packaging,a novel approach towards integrated magnetic bio-separator was designed.The magnetic field and the force on the bead were simulated and analyzed,leading to the optimization of the fabrication parameters of the micro-magnetic unit.The planar coil as an electromagnet was fabricated through electroplating on a single seed layer. The PDMS microfluidic channel was bonded on the inverse side after Si etching.The results presented in this paper provide a novel design and fabrication to approach a microfluidic bio-separation system with magnetic beads.
Based on flip-chip packaging, a novel approach to integrated magnetic bio-separator was designed. Magnetic field and the force on the bead were simulated and analyzed, leading to the optimization of the fabrication parameters of the micro-magnetic unit. coil as an electromagnet was fabricated through electroplating on a single seed layer. The PDMS microfluidic channel was bonded on the inverse side after Si etching. The results presented in this paper provide a novel design and fabrication to approach a microfluidic bio-separation system with magnetic beads