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我们测定了60例肾病综合征出血热(HFRS)患者的血清β_2—微球蛋白(β_2—MG)与血清尿素氮(BUN)、肌酐(Cr),结果表明,β_2—MG是检测HFRS对肾脏早期损害的敏感指标。 1 资料与方法 60例HFRS患者均符合1986年全国HFRS学术会议修订的诊断及分型标准,用酶联免疫法检测抗出血热病毒抗体阳性,HFRS免疫荧光抗体阳性。其中男43例,女17例;年龄15～58岁,平均32岁。发热期42例,休克期30例,少尿期41例,多尿期56例。恢复期42例。均无慢性肝、肾疾病,恶性肿瘤及其它慢性疾病史。病情各期均行血清β_2—MG、BUN、Cr检测并取30例健康人血清做对照。药盒
We measured the serum β_2-microglobulin (β_2-MG) and serum BUN and Cr levels in 60 patients with HFRS. The results showed that β_2-MG was an effective measure to detect the effect of HFRS on kidney Sensitive indicators of early damage. 1 Materials and Methods 60 cases of HFRS patients were in line with the 1986 National HFRS Conference revised diagnosis and classification criteria, using enzyme-linked immunosorbent assay for anti-haemorrhagic fever virus antibody positive, HFRS immunofluorescence antibody positive. Including 43 males and 17 females; aged 15 to 58 years, mean 32 years. 42 cases of fever, shock in 30 cases, oliguria in 41 cases, 56 cases of polyuria. Recovery period of 42 cases. No chronic liver, kidney disease, cancer and other chronic diseases history. Serum levels of β_2-MG, BUN, Cr were detected in all stages of the disease and 30 healthy human serum was taken as control. Kit