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目的 探讨血清前降钙素(PCT)检测在新生儿败血症中的应用价值。方法 对58例疑似新生儿败血症患儿采用半定量固相免疫测定法测定血清PCT水平,PCT水平分为<0.5 ng/ml,0.5-2.0 mg/ml,2.0-<10.0 ng/ml和≥10 mg/ml 4个等级,血清PCT>0.5 ng/ml为阳性阈值。结果 败血症组PCT阳性44例,阳性率75.9％,对照组仅1例阳性,阳性率5.5％,两组有显著差异。结论 血清PCT是新生儿败血症的重要诊断标准,可作为败血症预后判断及治疗监测的指标。
Objective To investigate the value of serum procalcitonin (PCT) detection in neonatal sepsis. Methods Serum PCT levels were measured by semi-quantitative solid-phase immunoassay in 58 children with suspected neonatal sepsis. PCT levels were divided into 0.5-2.0 mg / ml, 2.0- <10.0 ng / ml and ≥10 mg / ml 4 levels, serum PCT> 0.5 ng / ml as the positive threshold. Results Sepsis group PCT positive 44 cases, the positive rate of 75.9%, only 1 positive control group, the positive rate of 5.5%, the two groups were significantly different. Conclusion Serum PCT is an important diagnostic criteria for neonatal sepsis, which can be used as an indicator of prognosis and treatment monitoring of sepsis.