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目的探讨胰岛素增敏剂在多囊卵巢综合征治疗过程中的作用效果。方法 90例多囊卵巢综合征患者,随机分为对照组和观察组,各45例。对照组使用促性腺激素类药物进行诱发排卵;观察组在对照组的基础上对其增加使用胰岛素增敏剂,统计分析两组患者治疗前后的排卵和妊娠的情况,并比较治疗总有效率及不良反应情况。结果观察组的总有效率、妊娠率及排卵率均要高于对照组,差异有统计学意义(P<0.05);两组不良反应发生情况比较,差异无统计学意义(P>0.05)。结论在多囊卵巢综合征的治疗过程中,使用常规药物的基础上增加胰岛素增敏剂,可有效提高患者的妊娠率,改善总体治疗效果。同时,胰岛素增敏剂在临床上罕见不良反应发生,属于安全性较高的一类药物,值得继续探索推广。
Objective To investigate the effect of insulin sensitizer in the treatment of polycystic ovary syndrome. Methods Ninety patients with polycystic ovary syndrome were randomly divided into control group and observation group, with 45 cases in each group. The control group used gonadotropin drugs to induce ovulation. The observation group was given insulin sensitizer on the basis of the control group, and the ovulation and pregnancy before and after treatment were statistically analyzed. The total effective rate Adverse reactions. Results The total effective rate, pregnancy rate and ovulation rate in the observation group were higher than those in the control group (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion In the course of treatment of PCOS, the use of conventional drugs based on the increase of insulin sensitizers, can effectively improve the pregnancy rate of patients and improve the overall therapeutic effect. At the same time, insulin sensitizers rare clinical adverse reactions occur, belong to a class of drugs with higher safety, it is worth continuing to explore and promote.