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目的比较老年胃癌和中年胃癌的临床特点,为临床医生治疗胃癌提供参考。方法选取近3年来黑龙江省鹤岗矿业集团公司总医院收治的122例≥45岁的胃癌患者的临床资料,并进行回顾性分析,根据患者的年龄分为观察组和对照组。对两组患者的病因、发病症状、发病部位、治疗方法、生存率等方面进行比较。观察组患者的年龄≥65岁,对照组患者的年龄45~64岁。结果 122例患者中老年胃癌74例,占61%,中年胃癌48例,占39%。两组患者在性别上观察,男性发病率偏高,在TNM分期上观察组以Ⅲ、Ⅳ期为主,对照组以Ⅰ、Ⅱ期为主。在治疗类型上,观察组74例患者中54例采取药物治疗,20例患者采取手术治疗;对照组48例患者中手术治疗40例,8例为药物治疗。在生存率方面,对照组优于观察组,两组比较差异有统计学意义(P<0.05)。两组在发病症状及部位方面差异无统计学意义(P>0.05)。结论老年胃癌的发病率高于中年胃癌,老年胃癌的预后较差。但中年胃癌多为浸润型,易误诊,应引起重视,及早发现,及早治疗,提高存活率。
Objective To compare the clinical characteristics of elderly gastric cancer and middle-aged gastric cancer and provide reference for clinicians to treat gastric cancer. Methods The clinical data of 122 patients ≥45 years of gastric cancer who were treated in Hegang Longgang Hegang Mining Group General Hospital in the past three years were selected and analyzed retrospectively. The patients were divided into observation group and control group according to their age. The causes of the two groups of patients, the incidence of symptoms, the incidence of parts, treatment, survival rates and other aspects were compared. Patients in the observation group were ≥65 years old and patients in the control group were aged 45-64 years. Results Of the 122 patients, 74 were middle and old patients with gastric cancer, accounting for 61%, 48 were middle-aged patients with gastric cancer, accounting for 39%. The two groups of patients were sexually observed, the incidence of male high in the TNM staging group Ⅲ, Ⅳ-based, the control group Ⅰ, Ⅱ-based. In the type of treatment, 54 of the 74 patients in the observation group took medical treatment and 20 of them took surgical treatment. In the control group, 48 patients were treated by surgery and 8 were treated by drugs. In terms of survival rate, the control group was superior to the observation group, the difference between the two groups was statistically significant (P <0.05). There was no significant difference in symptom and location between the two groups (P> 0.05). Conclusion The incidence of gastric cancer in elderly patients is higher than that of middle-aged patients with gastric cancer. The prognosis of elderly patients with gastric cancer is poor. However, mostly middle-aged gastric cancer type of infiltration, misdiagnosis, should pay attention to early detection, early treatment, improve survival.