论文部分内容阅读
在一组年龄 10～ 15岁血压偏高及血压正常少年儿童 5年血压等随访的基础上 ,进行红细胞膜钠 /锂反转运、尿血管舒缓素及盐敏感性等测定。发现血压偏高及高血压家族史阳性少年儿童红细胞膜钠 /锂反转运速率显著增高 ,尿血管舒缓素排泄水平降低 ,且与血压及盐敏感性相关 ;钠 /锂反转运偏高或尿血管舒缓素偏低者过去 5年中血压上升幅度显著增大 ,其收缩压百分位数 (PSBP)多数上升或持续居于较高百分位次。提示红细胞膜钠 /锂反转运增强及尿血管舒缓素排泄低下作为高血压中间表现型 ,参与血压调节 ,在少年儿童高血压的发生发展中已起一定作用
Based on the follow-up of 5-year blood pressure of a group of children aged 10-15 years with high blood pressure and normal blood pressure, sodium-lithium translocation, urinary kallikrein and salt sensitivity were measured. Found that high blood pressure and hypertension family history of positive children erythrocyte membrane sodium / lithium translocation rate was significantly increased urinary vascular paraquat excretion decreased, and with blood pressure and salt sensitivity; sodium / lithium reverse transport high or In the past five years, the blood pressure increased significantly and the systolic blood pressure percentile (PSBP) increased or persisted to the higher percentile. Prompt red blood cell membrane sodium / lithium anti-transport enhancement and urinary vascular paraquat excretion is low as an intermediate phenotype of hypertension, involved in blood pressure regulation, in the occurrence and development of hypertension in children has played a role