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男性以智力低下为表现型的脆性X综合征将有丧失生育力的可能;而对女性则只是智商较低。至于脆性X智力低下的程度与生育力退变之间的关系如何目前还无法解释。据报道,多数男性携带者有生育力,为此智力低下型脆性X患者的生育力退变就不能简单地解释是获得了突变的结果。本文作者以前研究两例脆性X综合征患者的睾丸组织也发现有间质组织水肿、生育力退变以及精细胞明显变异损伤。对此作者提出:减数分裂后变化是否与第一次减数分裂染色体的
Men with impaired intelligence as a manifestation of Fragile X syndrome will have the possibility of loss of fertility; while women are only lower IQ. As for the relationship between the degree of fragile X mental retardation and fertility degeneration how can not explain. It has been reported that most male carriers have fertility and for this reason fertility degeneration in patients with mental retardation type fragile X can not be simply explained as a result of the mutation. The authors previously studied two patients with fragile X syndrome testicular tissue also found interstitial edema, fertility degeneration and significant changes in sperm cell damage. To this author put forward: whether changes after meiosis chromosome with the first meiosis