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本文报告引例指（趾）端恶性黑素瘤，临床Ⅱ期52．9％，临床Ⅲ期47．1％；同期伴有区域淋巴结转移68．6％；延误诊断78，4％；术前不恰当处置52．9％；术后3、5、10年生存率分别为41．7％，25％，6．3％；低于文献报道。提示，本病早期诊断和及时治疗是挽救生命的关键。早期诊断的关键在于医患的重视程度。禁忌术前不恰当的处置，术前切取活检后应尽早行根治术，切除活检不影响预后。手术首选远端截肢术，可最大限度地保存肢体功能而不影响预后，并辅以同时或异时的治疗性区域淋巴结清扫术，高位截肢和预防性的淋巴结清扫并不改善预后。
This article reports that the cited cases referred to medullary malignant melanoma, 52.9% of clinical phase II, 47.1% of clinical phase III; 68.6% of regional lymph node metastases were associated with the same period; 78,4% of delayed diagnosis; not before surgery 52.9% of the patients were properly treated. The postoperative survival rates at 3, 5, and 10 years were 41.7%, 25%, and 6.3%, respectively, which were lower than those reported in the literature. It is suggested that the early diagnosis and prompt treatment of this disease are the key to saving lives. The key to early diagnosis lies in the importance of doctors and patients. Contraindicated inappropriate preoperative treatment, radical biopsy should be performed as soon as possible after preoperative biopsy. Excisional biopsy does not affect the prognosis. Surgery is the preferred choice for distal amputation to maximize preservation of limb function without affecting prognosis, supplemented by simultaneous or allophageal therapeutic regional lymph node dissection. High amputation and prophylactic lymph node dissection do not improve prognosis.