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由于免疫学研究的迅速进展,使人们对由异常免疫反应所引起的某些疾病(如变态反应、自身免疫疾病、器官移植排斥反应等)有了进一步的了解。近年来,更由于各种新的免疫抑制剂的发现和临床应用,使免疫抑制疗法成为当前对这些疾病的重要治疗方法。但因为这些药物具有较大的毒性作用和副作用,因此深入了解药物的性能,严格掌握适应症,对避免盲目滥用和防止严重毒性作用与副作用的发生极为必要。一、什么是免疫抑制疗法和免疫抑制剂? 免疫抑制疗法是指应用某些免疫抑制剂以抑制体内异常免疫反应而达到治疗目的的一种疗法。常用的免疫抑制剂如下:
Because of the rapid progress in immunological research, people have gained a better understanding of certain diseases caused by abnormal immune responses (such as allergies, autoimmune diseases, organ transplant rejection, etc.). In recent years, due to the discovery and clinical application of various new immunosuppressive agents, immunosuppressive therapy has become an important treatment for these diseases. However, because these drugs have large toxic effects and side effects, it is essential to have an in-depth understanding of the properties of drugs and to strictly grasp indications in order to avoid blindly misusing and preventing severe toxic effects and side effects. First, what is immunosuppressive therapy and immunosuppressive agents? Immunosuppressive therapy refers to the use of certain immunosuppressive agents to inhibit abnormal immune responses in the body to achieve therapeutic purposes. The commonly used immunosuppressants are as follows: