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目的:研究Maspin及Ki67在结外鼻型NK/T细胞淋巴瘤中的表达及意义。方法:采用免疫组织化学方法检测34例结外鼻型NK/T细胞淋巴瘤及11例慢性鼻窦炎组织中Maspin及Ki67的表达。结果:Maspin在结外鼻型NK/T细胞淋巴瘤中呈低表达,Ki67在结外鼻型NK/T细胞淋巴瘤中呈高表达,Maspin与Ki67的表达之间呈负相关。结论:联合检测Maspin及Ki67对结外鼻型NK/T细胞淋巴瘤的诊断有重要意义。
Objective: To study the expression and significance of Maspin and Ki67 in extranodal nasal type NK / T cell lymphoma. Methods: Immunohistochemistry was used to detect the expression of Maspin and Ki67 in 34 cases of extranodal nasal type NK / T cell lymphoma and 11 cases of chronic sinusitis. Results: Maspin was low expressed in extranodal nasal type NK / T cell lymphoma, Ki67 was highly expressed in extranodal nasal type NK / T cell lymphoma, and Maspin was negatively correlated with Ki67 expression. Conclusion: The combined detection of Maspin and Ki67 is of great significance in the diagnosis of extranodal nasal type NK / T cell lymphoma.