论文部分内容阅读
目的:观察逍遥散加味联合西药治疗高血压病合并颈动脉粥样硬化患者的临床疗效。方法:将90例高血压病合并颈动脉粥样硬化,辨证属肝郁气滞证兼有血瘀者,随机分为治疗组和对照组,对照组44例以西药治疗,治疗组46例在西药治疗的基础上加服逍遥散加味方,2组均观察治疗6月。比较2组治疗前后颈动脉血管的内-中膜厚度(IMT)、颈动脉血流动力学、颈动脉粥样斑块的变化。结果:治疗后,2组症状积分均较治疗前降低(P<0.05),治疗组症状积分低于对照组(P<0.05)。2组颈动脉收缩期峰值流速(PSV)、舒张末期流速(EDV)、IMT、斑块面积值均较治疗前降低,差异均有统计学意义(P<0.05,P<0.01);治疗组各指标值均低于对照组(P<0.05)。结论:逍遥散加味联合西药治疗高血压病合并颈动脉粥样硬化肝郁气滞兼有血瘀证患者的作用优于单纯西药治疗者,具有改善患者临床症状,减小颈动脉IMT,缩小颈动脉粥样斑块的作用。
Objective: To observe the clinical efficacy of Xiaoyaosan flavored with western medicine in the treatment of patients with hypertension and carotid atherosclerosis. Methods: 90 cases of hypertension with carotid atherosclerosis, syndromes of liver qi stagnation both blood stasis were randomly divided into treatment group and control group, the control group of 44 patients treated with western medicine, 46 cases in the treatment group On the basis of Western medicine plus Xiaoyaosan flavored side, two groups were observed and treated in June. The IMT, carotid hemodynamics and carotid artery atherosclerotic plaque in two groups were compared before and after treatment. Results: After treatment, symptom scores of both groups were lower than those before treatment (P <0.05), symptom score of the treatment group was lower than that of the control group (P <0.05). The peak systolic velocity (PSV), end diastolic velocity (EDV), IMT and plaque area of the two groups were significantly lower than those before treatment (P <0.05, P <0.01) Index values were lower than the control group (P <0.05). Conclusions: Xiaoyao San flavoring combined with western medicine is superior to western medicine in treating hypertensive patients complicated with carotid atherosclerosis, liver stagnation and stagnation of liver-qi stagnation. It can improve clinical symptoms, reduce carotid IMT, narrow neck The role of atherosclerotic plaques.