论文部分内容阅读
目的 :探讨参麦注射液合纳洛酮治疗重度急性酒精中毒的临床疗效。方法 :5 3例患者 ,随机分为两组 :治疗组 2 8例 ,参麦注射液静脉滴注 ,纳洛酮静脉注射 ;对照组 2 5例 ,仅用纳洛酮静脉注射。结果 :治疗组疗效良好 ,而且心电异常发生率为 42 .9% ;对照组为 6 0 .0 %。心电异常的持续时间 ,治疗组明显缩短 ,有显著差异 (P <0 .0 5 )。两组的催醒时间虽有差异 ,但无统计学意义。结论 :参麦注射液合纳洛酮治疗重度急性酒精中毒疗效显著 ,且能避免因纳洛酮剂量偏大所致的不良反应发生。
Objective: To investigate the clinical efficacy of Shenmai injection combined with naloxone in the treatment of severe acute alcoholism. Methods: Fifty-three patients were randomly divided into two groups: treatment group 28 cases, Shenmai injection intravenous injection, naloxone intravenous injection; control group 25 cases, only naloxone intravenous injection. Results: The treatment group was effective, and the incidence of abnormal ECG was 42.9%; the control group was 60.0%. The duration of ECG abnormalities was significantly shorter in the treatment group (P <0.05). Although there are differences in wake time between the two groups, but no statistical significance. Conclusion: Shenmai injection combined with naloxone in the treatment of severe acute alcoholism has significant curative effect and can avoid the adverse reactions caused by the large dose of naloxone.