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目的：探讨氟比洛芬酯超前镇痛在直接喉镜下声带息肉摘除术的应用。方法择期行直接喉镜下声带息肉摘除术患者60例，ASAI-I级，随机分为两组，每组30例．Ⅰ组(观察组)患者全身麻醉诱导后静脉缓慢注射氟比洛芬酯注射液l00mg；Ⅱ组(对照组)不注射氟此洛芬酯注射液。分别记录两组患者术后2、4、8、16、24h的疼痛视觉模拟评分(VAS)；以及与麻醉镇痛相关的不良反应。结果观察组术后2、4、8、16、24hVAS明显低于对照组(P＜0.05)，两组与麻醉镇痛有关的不良反应之间比较无明显差异(P＞0.05)。结论氟比洛芬酯超前镇痛应用于直接喉镜下声带息肉摘除术，能有效缓解患者术后早期疼痛，减轻炎症反应，不良反应的发生率低。“,”Objective TO investigate the preemptive analgesia effect of Flurbiprofen Axetil in patient before divesting their Vocal cord polypus under direct laryngoscope. Method sixty patients ,ASAI-I grade,were randomly diverded into two group (n=30 each),group I (observation group) TO inject slowly Flurbiprofen Axetil l00mg to patient after induction of general anaesthesia ; group I (control group)not giving Flurbiprofen Axetil Injection.Analgesia score and the incidence of adverse reactions were measured by the method of visual analogue scale (VAS)at 2,4,8,16,and 24 hrs after operation. Result the VAS at 2,4,8,16,and 24 hrs of observation group were lower than control group (P0.05)Conclusion preemptive analgesia used for divesting their glottic polypus under direct laryngoscope was effectiveness to relieve prophase pain after operation , to ease Inflammatory reaction,to decrease incidence rate of adverse reaction.