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目的对手足口病合并神经系统损害患儿采用大剂量丙种球蛋白结合甲泼尼龙治疗之后,观察探讨治疗后的效果。方法随机抽取自2014年1月—2016年12月在该院接受手足口病合并神经系统损害的30例患儿,按照治疗方式将其分为对照组和观察组,对照组患儿的治疗方式为大剂量丙种球蛋白,观察组患儿的治疗方式为大剂量丙种球蛋白联合甲泼尼龙,治疗完成后对比分析两组患儿的治疗效果。结果由治疗所得到的结果来看,在治疗总有效率方面,对照组患儿显著低于观察组;在住院时间、神经系统症状的恢复时间以及发热持续时间方面,对照组患儿都明显高于观察组(P<0.05)。结论对手足口病合并神经系统损害患儿采用大剂量丙种球蛋白结合甲泼尼龙治疗之后,患儿的住院时间被显著的缩短,疗效非常显著,具有被推广应用的临床价值。
Objective To study the effect of treatment of HFMD complicated with neurological damage in children treated with high dose gamma globulin combined with methylprednisolone. Methods Thirty children with hand-foot-mouth disease complicated with nervous system were randomly selected in this hospital from January 2014 to December 2016. They were divided into control group, observation group and control group For high-dose gamma globulin, observation group treatment of children with high-dose gamma globulin and methylprednisolone, after treatment, the comparative analysis of two groups of children with treatment. Results From the results of treatment, children in the control group were significantly lower than the observation group in terms of the total effective rate of treatment. Children in the control group were significantly higher in hospitalization time, recovery time of neurological symptoms and duration of fever In the observation group (P <0.05). Conclusions The hospitalization time of children with foot-mouth disease and nervous system damage after treatment with high-dose gamma-globulin combined with methylprednisolone is significantly shortened and the curative effect is very significant. It has the clinical value of being popularized and applied.