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目的：探讨住院精神病患者综合护理干预效果。方法将179例住院精神病患者随机分为两组，研究组接受综合护理干预，对照组接受常规护理干预，观察8周。采用自拟调查表统计两组各类症状发生率，护士用住院病人观察量表评定护理干预效果。结果干预8周末研究组各类临床症状检出率显著低于对照组（ P＜0．05或0．01）；护士用住院病人观察量表评分显著优于对照组（P＜0．01）。结论综合护理干预有利于精神病患者各种精神症状的改善，对促进患者的临床康复具有积极作用。“,”Objective To explore the effect of comprehensive nursing intervention on psychiatric inpatients .Methods A total of 179 psychiatric patients were ran‐domly divide into two groups ,research group received comprehensive nursing intervention ,and control group did routine nursing intervention for 8 weeks .Incidences of various kinds of symptoms were added up with self‐made questionnaire ,nursing intervention effects assessed with the Nurses’ Observation Scale for Inpatient Evaluation (NOSIE) .Results After intervention the detection rates of various kinds of symp‐toms were significantly lower (P<0 .05 or 0 .01) and the NOSIE score was more advantageous in research than control group( P< 0 .01) .Conclusion Comprehensive nursing intervention is beneficial to the im‐provement of various kinds of mental symptoms and plays a positive role in promoting patients’ clinical re‐habilitation .