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研究对象为100例下肢深静脉血栓形成,随机予以皮下注射肝素钙或静滴肝素钠各50例。肝素钙剂量为250 IU/kg,每12小时1次,根据白陶王脑磷脂凝固时间(KCCT)调整剂量(维持KCCT于1.5~2倍正常值);肝素钠剂量为250 IU/kg,12小时滴完,根据KCCT调整剂量(维持KCCT于1.5~2倍正常值)。治疗14天后,改为口服华法林,维持凝血酶原时间于1.5~2倍正常值。肝素钙组中血栓完全消失者8例,缩小者29例,无变化者10例和增大者2例;肝素钠组则分别为1,23,10和13例(肝素钙组
The object of study was 100 cases of deep venous thrombosis of lower extremity. Fifty cases of heparin calcium or intravenous heparin sodium were injected subcutaneously. Heparin calcium dose of 250 IU / kg, once every 12 hours, according to white Tao Wang phospholipid coagulation time (KCCT) to adjust the dose (to maintain KCCT at 1.5 to 2 times the normal value); heparin dose of 250 IU / kg, 12 hours End of the drop, adjust the dose according to KCCT (to maintain KCCT at 1.5 to 2 times normal). After 14 days of treatment, oral warfarin was changed to maintain prothrombin time 1.5 to 2 times normal. Heparin calcium group, complete disappearance of thrombus in 8 cases, reduction in 29 cases, no change in 10 cases and increased in 2 cases; heparin sodium group were 1, 23, 10 and 13 cases (heparin group