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用放射免疫法分别测定了３４例鼻咽癌、１６例良性瘤、１２例炎症和１６例正常人外周血浆中前列环素（ＰＧＩ２）和血栓素Ａ２（ＴＸＡ２）的稳定代谢产物６－酮－前列腺素Ｆ１ａ。（６－ｋｅｔｏ－ＰＧＦ１ａ）和血栓素Ｂ２（ＴＸＢ２）的含量。结果显示鼻咽癌患者血浆ＴＸＢ２含量显著升高（Ｐ＜０．０１），ＰＧＩ２含量也有所增加；ＴＸＢ２／６－ｋｅｔｏ－ＰＧＦ１ａ比值显著增加（Ｐ＜０．０１）。鼻咽癌晚期患者血浆ＴＸＢ２含量显著高于早期患者（Ｐ＜０．０５）。提示ＰＧＩ２和ＴＸＡ２水平，尤其是ＴＸＡ２可作为鼻咽癌发展及转移的参考指标。
The stable metabolites of PGI2 and TXA2 in 34 cases of nasopharyngeal carcinoma, 16 cases of benign tumor, 12 cases of inflammation and 16 normal persons were detected by radioimmunoassay. Prostaglandin F1a. (6-keto-PGF1a) and thromboxane B2 (TXB2). The results showed that the content of TXB2 in plasma was significantly increased (P <0.01) and the content of PGI2 was also increased in patients with NPC. The ratio of TXB2 / 6-keto-PGF1a was significantly increased (P <0.01). The content of TXB2 in the patients with advanced nasopharyngeal carcinoma was significantly higher than that in the early stage (P <0.05). Suggesting that PGI2 and TXA2 levels, especially TXA2 can be used as a reference for the development and metastasis of nasopharyngeal carcinoma.