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目的了解入伍新兵人群中戊肝病毒IgM和IgG抗体的流行分布情况,为今后预防提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对北京军区空军近4年来自6个省市的353名入伍新兵血清样本进行了戊肝病毒IgM和IgG抗体检测,统计分析其阳性率。结果发现历年间入伍新兵血清戊肝病毒IgM均未检出;IgG抗体历年间有增高趋势,但差异无统计学意义,为3.18%～20.00%,平均10.20%;地区间差异有统计学意义,山西省(20.00%)和河北省(13.24%)较高,湖北省(3.18%)和北京市(4.65%)较低。结论入伍新兵人群中戊肝病毒IgG抗体阳性率为3.18%～20.00%,具有逐年增高趋势并有地区性差异;IgM均为阴性。所以,在新兵入伍期间,应采取加强检疫、增加抗-HEV检测项目和健康教育等有效预防措施。
Objective To understand the epidemiological distribution of hepatitis E virus IgM and IgG antibodies in recruits recruits, providing a scientific basis for future prevention. Methods Serum samples were collected from 353 soldiers recruited from 6 provinces and cities in the PLA Air Force for the past 4 years by enzyme-linked immunosorbent assay (ELISA) for the detection of hepatitis E virus IgM and IgG. Statistical analysis of the positive rate. The results showed that there was no detection of serine hepatitis E virus (IgM) in enrolled recruit soldiers during the previous years. The IgG antibody showed an increasing trend over the years, but the difference was not statistically significant (3.18% -20.00%, average 10.20%); Shanxi Province (20.00%) and Hebei Province (13.24%) are higher, while Hubei Province (3.18%) and Beijing City (4.65%) are lower. Conclusions The positive rate of hepatitis E virus IgG in recruits was 3.18% -20.00%, with a trend of increasing year by year and regional differences; IgM was negative. Therefore, during recruiting new recruits, effective quarantine measures should be taken to increase effective preventive measures such as anti-HEV test items and health education.