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测定脑出血急性期患者病灶及血清中肿瘤坏死因子（ＴＮＦ）含量。结果表明，两者含量均显著高于对照组血清中含量，并且病灶中ＴＮＦ含量显著高于患者血清中含量。在此基础上，结合病灶和血清中与ＴＮＦ生物学功能有关物质ＮＯ和ＭＤＡ的变化，探讨脑出血急性期病灶中ＴＮＦ升高对病理变化的影响。
Tumor necrosis factor (TNF) levels were determined in patients with acute cerebral hemorrhage and in serum. The results showed that the content of both were significantly higher than that of the control group, and the content of TNF in the lesion was significantly higher than that in the serum. On this basis, combined with the changes of TNF and TNF-related biological substances NO and MDA in the lesion and serum to explore the impact of TNF in the pathogenesis of acute cerebral hemorrhage on pathological changes.