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目的:探讨血浆D-二聚体测定在肺栓塞患者诊断中的价值,提高检测水平。方法:将2009年2月~2013年1月我科收治的37例疑似急性肺栓塞患者作为试验组,选取同期于我院作体检的72例健康人群作为对照组,抽血化验D-二聚体,记录并做回顾性分析。结果:试验组D-二聚体浓度高于对照组且差异具有统计学意义(P<0.05),试验组阳性率86.48%,灵敏度为90.32%,特异度为33.33%。结论:血浆D-二聚体测定对于诊断肺栓塞的阳性率及灵敏度均较高,对于诊断具有重要指导意义,而特异度差,可作为排除肺栓塞的首选试验,值得进一步研究推广。
Objective: To investigate the value of plasma D-dimer in the diagnosis of patients with pulmonary embolism and improve the detection level. Methods: From February 2009 to January 2013, 37 patients with suspected acute pulmonary embolism who were admitted to our department were selected as the experimental group. Totally 72 healthy people undergoing physical examination in our hospital were selected as the control group. Body, record and do retrospective analysis. Results: The concentration of D-dimer in test group was higher than that in control group (P <0.05). The positive rate of test group was 86.48%, the sensitivity was 90.32% and the specificity was 33.33%. Conclusions: The positive rate and sensitivity of plasma D-dimer in the diagnosis of pulmonary embolism are high, which is of great guiding significance for diagnosis and poor specificity, which can be used as the first choice to exclude pulmonary embolism. It is worth further study and promotion.